A few selected have been able to touch me with joy, respect and other positive feelings though. Some honorable mentions are Hajime no Ippo (great motivating story about strength) , Texhnolyze (dystopian science fiction about prosthesis and has a dark story) , Legend of the Galactic Heroes (if you want a genuine epic story, look no further) and my second favorite Anime, Monster (the most brilliant and darkest thriller that never let go of me).
But the one and only currently airing series that has practically never lost it's magic during it's countless episodes is One Piece, one of if not the most famous Anime in Japan available. As to why it is my favorite Anime I have seen so far, there are many reasons for that which I am about to describe, but it is most of all about an enormous story that if possible, I would had probably very much liked to live in.
With countless of background story, mysteries, twists and lore, One Piece already has a lot to offer before even beginning on the rest of it's awesomeness. The series tends to have a natural flow of eagerness towards me because either it is busy laughing my ass out, or it's thrilling me with the craziest and entertaining fights, or it's using drama and introductions to remind us that the situations have depth to them plus the story has to carry on and cannot hang too long onto the already established things.
Humor is nothing new in One Piece, as each episode almost ALWAYS has atleast one funny joke for the viewer to enjoy. And that is something really impressive, considering the vast amount of episodes and situations already available. Some of the oldest music from the earlier airings of the Anime are now, like ten years later, STILL playing, and it is still effective to listen to. The opening songs are sometimes very effective and make me excited for the current arc (a temporary storyline that is split up into smaller sections).
Perhaps the best thing about One Piece are it's countless interesting characters. From a lovable, strong protagonist team to the best villains I have ever witnessed in Anime, to the even more countless characters that only appear briefly or until an arc is over, literally, One Piece has atleast one character for everyone to enjoy. I could probably talk hours already about each famous character and their development, but I am moving on now to explain more about why I love this series.
The series has done very succesfully so far by being as original as possible with each new arc appearing, and the world of pirates keeps growing as we continue to watch this beyond epic voyage of romance happening. Unlike famous Animes such as Naruto or Bleach, One Piece never shows bad repetitiveness and fillers (filler ins exclusively for the Anime in order to give the creator of the Manga more time to continue the story) are very rarely unwatchable. It also is leaps beyond them with originality and unlike them, it seems that One Piece has only just started regarding it's huge story to tell.
It's a sad fact that an English translation raped the magic of One Piece to the West, by changing and censoring A LOT of stuff, cutting away entire arcs and making stupid replacements instead. Fortunately, the Japanese version will always be available and if you are curious to start watching this giant series then by all means watch the original version from the start. Get through the introduction episodes and arcs, and once you have arrived around say, Episode 99, then you should be able to start really appreciating it. (beware of spoilers constantly though)
One Piece deserves all of the praise it is getting for making a wonderful fantasy tale about the age of pirates, and I will definitely keep watching this amazing series and let myself get engulfed by all of it.